Tribulus terrestris
NIH’s LiverTox gives a usual daily dose of 250 to 750 mg and is blunt about efficacy: in controlled trials, improvements in sexual function were no greater with Tribulus terrestris extracts than with placebo.
Liver-injury likelihood score E*. Case reports include a man whose creatinine rose from 1.1 to 3.1 mg/dL, and a man who drank two litres of tribulus water daily and developed seizures with an ALT forty times the upper limit.